TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction.

Topaloglu, A Kemal

TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction. [electronic resource] - Nature genetics Mar 2009 - 354-358 p. digital

Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't

1546-1718

10.1038/ng.306 doi


Amino Acid Sequence
Chromosomes, Human, Pair 4
DNA Mutational Analysis
Family
Gonads--metabolism
Humans
Hypogonadism--genetics
Kisspeptins
Models, Biological
Mutation--physiology
Neurokinin B--genetics
Neurons--metabolism
Pedigree
Receptors, Neurokinin-3--genetics
Reproduction--genetics
Sequence Homology, Amino Acid
Tumor Suppressor Proteins--metabolism