17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse.

Tokui, Keisuke

17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse. [electronic resource] - Human molecular genetics Mar 2009 - 898-910 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1460-2083

10.1093/hmg/ddn419 doi


Animals
Benzoquinones--administration & dosage
Disease Models, Animal
Lactams, Macrocyclic--administration & dosage
Mice
Mice, Transgenic
Motor Neurons--drug effects
Muscular Atrophy, Spinal--drug therapy
Peptides--metabolism
Proteasome Endopeptidase Complex--genetics
Receptors, Androgen--genetics
Ubiquitin--genetics