Obesity and hypertension have differing oxidant handling molecular pathways in age-related chronic kidney disease.

Percy, C J

Obesity and hypertension have differing oxidant handling molecular pathways in age-related chronic kidney disease. [electronic resource] - Mechanisms of ageing and development Mar 2009 - 129-38 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0047-6374

10.1016/j.mad.2008.10.003 doi


AMP-Activated Protein Kinases--metabolism
Adiposity
Age Factors
Aging--metabolism
Animals
Autophagy
Body Weight
Chronic Disease
Disease Models, Animal
Extracellular Signal-Regulated MAP Kinases--metabolism
Fibrosis
Forkhead Transcription Factors--metabolism
Heme Oxygenase (Decyclizing)--metabolism
Hypertension--metabolism
Kidney--metabolism
Kidney Diseases--metabolism
L-Lactate Dehydrogenase--blood
Male
NF-kappa B--metabolism
Nerve Tissue Proteins--metabolism
Obesity--metabolism
Oxidants--metabolism
Oxidative Stress
Phosphorylation
Proto-Oncogene Proteins c-akt--metabolism
Proto-Oncogene Proteins c-bcl-2--metabolism
Rats
Rats, Inbred SHR
Rats, Inbred WKY
Shc Signaling Adaptor Proteins--metabolism
Signal Transduction
Src Homology 2 Domain-Containing, Transforming Protein 1
bcl-2-Associated X Protein--metabolism