Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients.

Kuntzen, Thomas

Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients. [electronic resource] - Hepatology (Baltimore, Md.) Dec 2008 - 1769-78 p. digital

Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1527-3350

10.1002/hep.22549 doi


Antiviral Agents--pharmacology
Carbamates--pharmacology
Cohort Studies
Drug Resistance, Viral--genetics
Female
Genetic Testing
Hepacivirus--enzymology
Hepatitis C--blood
Humans
Macrocyclic Compounds--pharmacology
Male
Mutation--genetics
Oligopeptides--pharmacology
Phenylthiourea--analogs & derivatives
Phylogeny
Proline--analogs & derivatives
Protease Inhibitors--therapeutic use
Quinolines--pharmacology
Thiazoles--pharmacology
Viral Load
Viral Nonstructural Proteins--antagonists & inhibitors