Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP.

Chen, Yei-Tsung

Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP. [electronic resource] - Molecular and cellular biology Feb 2009 - 736-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1098-5549

10.1128/MCB.01313-08 doi


Animals
Blood Vessels--abnormalities
Carrier Proteins--metabolism
Crosses, Genetic
Embryo Loss--genetics
Embryo, Mammalian--abnormalities
Embryonic Development
Extraembryonic Membranes--abnormalities
Female
Gene Deletion
Gene Expression Regulation, Developmental
Gene Targeting
Heterozygote
Humans
Intracellular Signaling Peptides and Proteins
Male
Mice
Mice, Knockout
Protein Subunits--deficiency
Transcription, Genetic
Transcriptional Elongation Factors
Transgenes