Acetyl-L-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain.

Alves, E

Acetyl-L-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain. [electronic resource] - Neuroscience Jan 2009 - 514-23 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0306-4522

10.1016/j.neuroscience.2008.10.041 doi


Acetylcarnitine--therapeutic use
Animals
Body Weight--drug effects
Brain--pathology
Cyclooxygenase 1--genetics
DNA, Mitochondrial--metabolism
Fever--chemically induced
Hallucinogens--toxicity
Hydroxyindoleacetic Acid--metabolism
Lipid Peroxidation--drug effects
Membrane Proteins--genetics
Mitochondria--drug effects
Mitochondrial Diseases--etiology
N-Methyl-3,4-methylenedioxyamphetamine--toxicity
NADH Dehydrogenase--metabolism
Protein Carbonylation--drug effects
Rats
Rats, Wistar
Serotonin--metabolism
Vitamin B Complex--therapeutic use