Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice.

Meyer, T

Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice. [electronic resource] - Journal of thrombosis and haemostasis : JTH Jan 2009 - 171-81 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1538-7836

10.1111/j.1538-7836.2008.03212.x doi


Animals
Antibodies, Monoclonal--adverse effects
Antibodies, Monoclonal, Humanized
Antigen-Antibody Complex--adverse effects
Bevacizumab
Heparin--physiology
Mice
Mice, Transgenic
Platelet Activation--drug effects
Receptors, IgG--genetics
Thrombosis--chemically induced
Vascular Endothelial Growth Factor A--immunology