Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1.

Li, Xiaoyu

Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1. [electronic resource] - The Journal of experimental medicine Nov 2008 - 2851-61 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1540-9538

10.1084/jem.20081561 doi


Adult
Animals
Bone Marrow Transplantation
Cell Line, Tumor
Cell Transformation, Neoplastic
Gene Expression Profiling
Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Genes, myc
Genetic Vectors
Genomic Instability
Hematopoietic Stem Cells--cytology
Humans
Karyotyping
Mice
Mice, Inbred BALB C
Mice, Nude
Oligonucleotide Array Sequence Analysis
Phenotype
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--genetics
Proto-Oncogene Proteins c-myc--genetics
Receptor, Notch1--genetics
Receptors, Antigen, T-Cell, alpha-beta--genetics
Tumor Suppressor Protein p53--genetics