Uric acid stimulates endothelin-1 gene expression associated with NADPH oxidase in human aortic smooth muscle cells.

Chao, Hung-hsing

Uric acid stimulates endothelin-1 gene expression associated with NADPH oxidase in human aortic smooth muscle cells. [electronic resource] - Acta pharmacologica Sinica Nov 2008 - 1301-12 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1745-7254

10.1111/j.1745-7254.2008.00877.x doi


Aorta, Thoracic--cytology
Cell Line
Cell Proliferation--drug effects
Chloramphenicol O-Acetyltransferase--genetics
Endothelin-1--biosynthesis
Extracellular Signal-Regulated MAP Kinases--metabolism
Humans
Myocytes, Smooth Muscle--drug effects
NADPH Oxidases--physiology
RNA--biosynthesis
RNA, Small Interfering--genetics
Reactive Oxygen Species--metabolism
Stimulation, Chemical
Transfection
Uric Acid--pharmacology