Transcriptional repression of microRNA genes by PML-RARA increases expression of key cancer proteins in acute promyelocytic leukemia.

Saumet, Anne

Transcriptional repression of microRNA genes by PML-RARA increases expression of key cancer proteins in acute promyelocytic leukemia. [electronic resource] - Blood Jan 2009 - 412-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1528-0020

10.1182/blood-2008-05-158139 doi


Antineoplastic Agents--therapeutic use
Arsenic--therapeutic use
Biomarkers, Tumor--biosynthesis
Cell Adhesion Molecules--biosynthesis
Cell Line, Tumor
Gene Expression Regulation, Leukemic--drug effects
Homeodomain Proteins--biosynthesis
Humans
Leukemia, Promyelocytic, Acute--drug therapy
MicroRNAs--biosynthesis
Oncogene Proteins, Fusion--genetics
RNA, Neoplasm--biosynthesis
Transcription, Genetic--drug effects
Tretinoin--therapeutic use