The design, synthesis, and evaluation of coumarin ring derivatives of the novobiocin scaffold that exhibit antiproliferative activity.

Donnelly, Alison C

The design, synthesis, and evaluation of coumarin ring derivatives of the novobiocin scaffold that exhibit antiproliferative activity. [electronic resource] - The Journal of organic chemistry Nov 2008 - 8901-20 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1520-6904

10.1021/jo801312r doi


Cell Line, Tumor
Cell Proliferation--drug effects
Coumarins--chemistry
Drug Design
Humans
Naphthalenes--chemistry
Novobiocin--chemical synthesis
Quinolines--chemistry