A dietary anthocyanidin delphinidin induces apoptosis of human prostate cancer PC3 cells in vitro and in vivo: involvement of nuclear factor-kappaB signaling.

Hafeez, Bilal Bin

A dietary anthocyanidin delphinidin induces apoptosis of human prostate cancer PC3 cells in vitro and in vivo: involvement of nuclear factor-kappaB signaling. [electronic resource] - Cancer research Oct 2008 - 8564-72 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1538-7445

10.1158/0008-5472.CAN-08-2232 doi


Animals
Anthocyanins--pharmacology
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Division--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Cyclin D1--antagonists & inhibitors
DNA--metabolism
Dose-Response Relationship, Drug
G2 Phase--drug effects
Humans
I-kappa B Kinase--antagonists & inhibitors
Ki-67 Antigen--analysis
Male
Mice
Mice, Nude
NF-kappa B--metabolism
Phosphorylation
Poly(ADP-ribose) Polymerases--metabolism
Proliferating Cell Nuclear Antigen--analysis
Prostatic Neoplasms--drug therapy
Proto-Oncogene Proteins c-bcl-2--analysis
Signal Transduction--physiology
bcl-2-Associated X Protein--analysis