Ro 42-5892 is a potent orally active renin inhibitor in primates.

Fischli, W

Ro 42-5892 is a potent orally active renin inhibitor in primates. [electronic resource] - Hypertension (Dallas, Tex. : 1979) Jul 1991 - 22-31 p. digital

Publication Type: Journal Article

0194-911X

10.1161/01.hyp.18.1.22 doi


Administration, Oral
Analysis of Variance
Angiotensin I--blood
Angiotensin II--blood
Angiotensin-Converting Enzyme Inhibitors
Animals
Antihypertensive Agents
Blood Pressure--drug effects
Callitrichinae
Cattle
Cilazapril
Dogs
Dose-Response Relationship, Drug
Heart Rate--drug effects
Humans
Imidazoles
Immunoradiometric Assay
Kidney--physiology
Minoxidil--pharmacology
Nephrectomy
Pyridazines--pharmacology
Rats
Regression Analysis
Renin--antagonists & inhibitors
Saimiri
Sodium Chloride--pharmacology
Stereoisomerism