Neutrophil-mediated activation of epithelial protease-activated receptors-1 and -2 regulates barrier function and transepithelial migration.

Chin, Alex C

Neutrophil-mediated activation of epithelial protease-activated receptors-1 and -2 regulates barrier function and transepithelial migration. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Oct 2008 - 5702-10 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1550-6606

10.4049/jimmunol.181.8.5702 doi


Cathepsin G
Cathepsins--pharmacology
Cell Movement--drug effects
Cells, Cultured
Chemotactic Factors--immunology
Coculture Techniques
Gene Expression Regulation--drug effects
Humans
Inflammatory Bowel Diseases--immunology
Intestinal Mucosa--immunology
Myeloblastin--pharmacology
Neutrophil Infiltration--drug effects
Neutrophils--immunology
Pancreatic Elastase--pharmacology
Permeability--drug effects
Receptor, PAR-1--immunology
Receptor, PAR-2--antagonists & inhibitors
Serine Endopeptidases--pharmacology
Signal Transduction--drug effects
Substrate Specificity
Tight Junctions--immunology
Platelet Aggregation Inhibitors