Inhibition of Hsp90 leads to cell cycle arrest and apoptosis in human malignant pleural mesothelioma.

Okamoto, Junichi

Inhibition of Hsp90 leads to cell cycle arrest and apoptosis in human malignant pleural mesothelioma. [electronic resource] - Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer Oct 2008 - 1089-95 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1556-1380

10.1097/JTO.0b013e3181839693 doi


Apoptosis--drug effects
Benzoquinones--pharmacology
Blotting, Western
Cell Cycle--drug effects
Cell Proliferation--drug effects
HSP90 Heat-Shock Proteins--antagonists & inhibitors
Humans
Inhibitor of Apoptosis Proteins
Lactams, Macrocyclic--pharmacology
Mesothelioma--drug therapy
Microtubule-Associated Proteins--metabolism
Pleural Neoplasms--drug therapy
Proto-Oncogene Proteins c-akt--metabolism
Survivin
Tumor Cells, Cultured