The octarepeat region of prion protein, but not the TM1 domain, is important for the antioxidant effect of prion protein.

Malaisé, Muriel

The octarepeat region of prion protein, but not the TM1 domain, is important for the antioxidant effect of prion protein. [electronic resource] - Free radical biology & medicine Dec 2008 - 1622-30 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0891-5849

10.1016/j.freeradbiomed.2008.08.024 doi


Animals
Antioxidants--pharmacology
Copper--metabolism
HeLa Cells
Humans
Hydrogen Peroxide--pharmacology
Membrane Potential, Mitochondrial--drug effects
Mice
Neuroblastoma--metabolism
Oxidants--pharmacology
Oxidative Stress--drug effects
Prions--metabolism
Protein Structure, Tertiary
Reactive Oxygen Species--metabolism
Repetitive Sequences, Nucleic Acid
Sequence Deletion