Activated epidermal growth factor receptor as a novel target in pancreatic cancer therapy.
Harsha, H C
Activated epidermal growth factor receptor as a novel target in pancreatic cancer therapy. [electronic resource] - Journal of proteome research Nov 2008 - 4651-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1535-3893
10.1021/pr800139r doi
Animals
Biomarkers, Tumor
Cell Line, Tumor
Enzyme Activation--drug effects
ErbB Receptors--antagonists & inhibitors
Erlotinib Hydrochloride
Female
Gene Expression Profiling
Gene Expression Regulation, Enzymologic
Humans
Immunohistochemistry
Mice
Mice, Nude
Pancreatic Neoplasms--drug therapy
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--genetics
Proteomics--methods
Quinazolines--pharmacology
Substrate Specificity
Tumor Burden--drug effects
Xenograft Model Antitumor Assays
Activated epidermal growth factor receptor as a novel target in pancreatic cancer therapy. [electronic resource] - Journal of proteome research Nov 2008 - 4651-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1535-3893
10.1021/pr800139r doi
Animals
Biomarkers, Tumor
Cell Line, Tumor
Enzyme Activation--drug effects
ErbB Receptors--antagonists & inhibitors
Erlotinib Hydrochloride
Female
Gene Expression Profiling
Gene Expression Regulation, Enzymologic
Humans
Immunohistochemistry
Mice
Mice, Nude
Pancreatic Neoplasms--drug therapy
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--genetics
Proteomics--methods
Quinazolines--pharmacology
Substrate Specificity
Tumor Burden--drug effects
Xenograft Model Antitumor Assays