Mechanisms of proteasome inhibitor action and resistance in cancer.

McConkey, David J

Mechanisms of proteasome inhibitor action and resistance in cancer. [electronic resource] - Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy - 164-79 p. digital

Publication Type: Journal Article; Review

1532-2084

10.1016/j.drup.2008.08.002 doi


Animals
Antineoplastic Agents--therapeutic use
Apoptosis--drug effects
Cysteine Proteinase Inhibitors--therapeutic use
Drug Resistance, Neoplasm
Humans
NF-kappa B--metabolism
Neoplasms--drug therapy
Proteasome Endopeptidase Complex--metabolism
Proteasome Inhibitors
Protein Folding--drug effects
Treatment Outcome