Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis.

Carmona, Guillaume

Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis. [electronic resource] - Blood Jan 2009 - 488-97 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1528-0020

10.1182/blood-2008-02-138438 doi


Adaptor Proteins, Signal Transducing
Animals
Apoptosis Regulatory Proteins
Cell Adhesion--physiology
Cell Movement--physiology
Endothelial Cells--cytology
Fibroblast Growth Factors--metabolism
Focal Adhesion Kinase 1--metabolism
GTPase-Activating Proteins--metabolism
Gene Silencing
Hindlimb--blood supply
Humans
Integrin beta1--metabolism
Ischemia--enzymology
Mice
Mice, Knockout
Monomeric GTP-Binding Proteins--metabolism
Neovascularization, Physiologic--physiology
Phosphorylation--physiology
Proto-Oncogene Proteins c-akt
Umbilical Veins--cytology
rap GTP-Binding Proteins--metabolism
rap1 GTP-Binding Proteins--metabolism