Human-specific gain of function in a developmental enhancer.

Prabhakar, Shyam

Human-specific gain of function in a developmental enhancer. [electronic resource] - Science (New York, N.Y.) Sep 2008 - 1346-50 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1095-9203

10.1126/science.1159974 doi


Animals
Base Sequence
Binding Sites
Body Patterning--genetics
Conserved Sequence
Embryonic Development
Enhancer Elements, Genetic
Evolution, Molecular
Extremities--embryology
Gene Expression Profiling
Gene Expression Regulation, Developmental
Humans
Limb Buds--embryology
Macaca mulatta--genetics
Mice
Mice, Transgenic
Molecular Sequence Data
Mutation
PAX9 Transcription Factor--metabolism
Pan troglodytes--genetics
Selection, Genetic
Transcription Factors--metabolism