Insulin suppresses LPS-induced iNOS and COX-2 expression and NF-kappaB activation in alveolar macrophages.

Martins, Joilson O

Insulin suppresses LPS-induced iNOS and COX-2 expression and NF-kappaB activation in alveolar macrophages. [electronic resource] - Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2008 - 279-86 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1421-9778

10.1159/000149806 doi


Animals
Cyclooxygenase 2--biosynthesis
Dinoprostone--biosynthesis
Enzyme Induction--drug effects
I-kappa B Proteins--metabolism
Insulin--pharmacology
Lipopolysaccharides--pharmacology
Macrophages, Alveolar--drug effects
Male
NF-kappa B--metabolism
Nitric Oxide--biosynthesis
Nitric Oxide Synthase Type II--biosynthesis
Phosphorylation--drug effects
Rats
Rats, Wistar