Synthesis and biological evaluation of indolyl bisphosphonates as anti-bone resorptive and anti-leishmanial agents.

Singh, Uma Sharan

Synthesis and biological evaluation of indolyl bisphosphonates as anti-bone resorptive and anti-leishmanial agents. [electronic resource] - Bioorganic & medicinal chemistry Sep 2008 - 8482-91 p. digital

Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't

1464-3391

10.1016/j.bmc.2008.08.024 doi


Alendronate--pharmacology
Animals
Apoptosis--drug effects
Bone Density Conservation Agents--chemical synthesis
Bone Resorption--metabolism
Cell Proliferation--drug effects
Cells, Cultured
Diphosphonates--chemical synthesis
Indoles--chemical synthesis
Leishmania--drug effects
Mice
Osteoclasts--metabolism
Structure-Activity Relationship