Interaction of the active metabolite of prasugrel, R-138727, with cysteine 97 and cysteine 175 of the human P2Y12 receptor.

Algaier, I

Interaction of the active metabolite of prasugrel, R-138727, with cysteine 97 and cysteine 175 of the human P2Y12 receptor. [electronic resource] - Journal of thrombosis and haemostasis : JTH Nov 2008 - 1908-14 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1538-7836

10.1111/j.1538-7836.2008.03136.x doi


Animals
Binding Sites
CHO Cells
Cricetinae
Cricetulus
Cysteine--metabolism
Humans
Piperazines--metabolism
Platelet Aggregation Inhibitors
Prasugrel Hydrochloride
Receptors, Purinergic P2--metabolism
Receptors, Purinergic P2Y12
Thiophenes--metabolism
Transduction, Genetic