mu-Opioid agonists inhibit the enhanced intracellular Ca(2+) responses in inflammatory activated astrocytes co-cultured with brain endothelial cells.

Hansson, E

mu-Opioid agonists inhibit the enhanced intracellular Ca(2+) responses in inflammatory activated astrocytes co-cultured with brain endothelial cells. [electronic resource] - Neuroscience Sep 2008 - 1237-49 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0306-4522

10.1016/j.neuroscience.2008.04.027 doi


3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer--pharmacology
Analgesics, Non-Narcotic--pharmacology
Analgesics, Opioid--pharmacology
Analysis of Variance
Animals
Animals, Newborn
Astrocytes--drug effects
Brain--cytology
Calcium--metabolism
Cells, Cultured
Coculture Techniques--methods
Endothelial Cells--physiology
Glial Fibrillary Acidic Protein--metabolism
Leptin--pharmacology
Lipopolysaccharides--pharmacology
Membrane Potentials--drug effects
Naloxone--pharmacology
Narcotic Antagonists--pharmacology
Patch-Clamp Techniques
Rats
Receptors, Opioid, mu--metabolism
Serotonin--pharmacology
Substance P--pharmacology
Time Factors
von Willebrand Factor--immunology