G-protein-coupled receptor GPR49 is up-regulated in basal cell carcinoma and promotes cell proliferation and tumor formation.

Tanese, Keiji

G-protein-coupled receptor GPR49 is up-regulated in basal cell carcinoma and promotes cell proliferation and tumor formation. [electronic resource] - The American journal of pathology Sep 2008 - 835-43 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1525-2191

10.2353/ajpath.2008.071091 doi


Animals
Carcinoma, Basal Cell--metabolism
Cell Proliferation
Gene Expression
Gene Expression Profiling
Hedgehog Proteins--physiology
Humans
In Situ Hybridization
Mice
RNA, Messenger--analysis
Receptors, G-Protein-Coupled--biosynthesis
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--physiology
Skin Neoplasms--metabolism
Up-Regulation