PI3K-Akt signaling regulates basal, but MAP-kinase signaling regulates radiation-induced XRCC1 expression in human tumor cells in vitro.

Toulany, Mahmoud

PI3K-Akt signaling regulates basal, but MAP-kinase signaling regulates radiation-induced XRCC1 expression in human tumor cells in vitro. [electronic resource] - DNA repair Oct 2008 - 1746-56 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1568-7864

10.1016/j.dnarep.2008.06.017 doi


Cell Line, Tumor
DNA Breaks, Double-Stranded--drug effects
DNA Repair--drug effects
DNA-Activated Protein Kinase--deficiency
DNA-Binding Proteins--metabolism
ErbB Receptors--metabolism
Extracellular Signal-Regulated MAP Kinases--metabolism
Humans
MAP Kinase Signaling System--drug effects
Mitogen-Activated Protein Kinases--metabolism
Phosphatidylinositol 3-Kinases--metabolism
Phosphoinositide-3 Kinase Inhibitors
Protein Binding--drug effects
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
Radiation, Ionizing
Recombinant Fusion Proteins--metabolism
Recombination, Genetic--drug effects
X-ray Repair Cross Complementing Protein 1