Sumoylation of amyloid precursor protein negatively regulates Abeta aggregate levels.

Zhang, Yu-Qian

Sumoylation of amyloid precursor protein negatively regulates Abeta aggregate levels. [electronic resource] - Biochemical and biophysical research communications Oct 2008 - 673-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1090-2104

10.1016/j.bbrc.2008.07.109 doi


Alzheimer Disease--metabolism
Amyloid Precursor Protein Secretases--metabolism
Amyloid beta-Peptides--genetics
Amyloid beta-Protein Precursor--genetics
Endoplasmic Reticulum--enzymology
HeLa Cells
Humans
Lysine--genetics
Protein Processing, Post-Translational
Small Ubiquitin-Related Modifier Proteins--metabolism
Transfection
Ubiquitin-Conjugating Enzymes--genetics
Ubiquitin-Conjugating Enzyme UBC9