Biotransformation of the chemopreventive agent 2',4',4-trihydroxychalcone (isoliquiritigenin) by UDP-glucuronosyltransferases.

Guo, Jian

Biotransformation of the chemopreventive agent 2',4',4-trihydroxychalcone (isoliquiritigenin) by UDP-glucuronosyltransferases. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Oct 2008 - 2104-12 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1521-009X

10.1124/dmd.108.021857 doi


Aldehyde Reductase--antagonists & inhibitors
Anticarcinogenic Agents--pharmacokinetics
Biotransformation
Chalcones--pharmacokinetics
Chromatography, High Pressure Liquid
Enzyme Inhibitors--pharmacokinetics
Glucuronosyltransferase--metabolism
Humans
Kidney--enzymology
Liver--enzymology
Mass Spectrometry
Microsomes--enzymology
Spectrophotometry, Ultraviolet