YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway.

Wu, S Y

YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway. [electronic resource] - British journal of pharmacology Oct 2008 - 505-13 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0007-1188

10.1038/bjp.2008.292 doi


Animals
Apoptosis--drug effects
Carcinoma, Renal Cell--drug therapy
Caspase 3--drug effects
Caspase 8--drug effects
Chromatin--drug effects
Dose-Response Relationship, Drug
Enzyme Activators--administration & dosage
Fas Ligand Protein--drug effects
G1 Phase--drug effects
Humans
Indazoles--administration & dosage
JNK Mitogen-Activated Protein Kinases--drug effects
Male
Mice
Mice, Inbred BALB C
Mice, Nude
Phosphorylation--drug effects
fas Receptor--drug effects