Effect of vaginal distention on elastic fiber synthesis and matrix degradation in the vaginal wall: potential role in the pathogenesis of pelvic organ prolapse.

Rahn, D D

Effect of vaginal distention on elastic fiber synthesis and matrix degradation in the vaginal wall: potential role in the pathogenesis of pelvic organ prolapse. [electronic resource] - American journal of physiology. Regulatory, integrative and comparative physiology Oct 2008 - R1351-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0363-6119

10.1152/ajpregu.90447.2008 doi


Animals
Biomechanical Phenomena
Catheterization
Elastic Tissue--metabolism
Electrophoresis, Polyacrylamide Gel
Enzyme Precursors--metabolism
Extracellular Matrix--metabolism
Extracellular Matrix Proteins--genetics
Female
Gelatinases--metabolism
Male
Matrix Metalloproteinase 2--metabolism
Matrix Metalloproteinase 9--metabolism
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Mice, Knockout
Pelvic Floor--pathology
Perineum--pathology
Pregnancy
Pregnancy Complications--etiology
Recombinant Proteins--genetics
Tropoelastin--metabolism
Uterine Prolapse--etiology
Vagina--injuries