Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart.

Hothi, Sandeep S

Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart. [electronic resource] - Pflugers Archiv : European journal of physiology Nov 2008 - 253-70 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0031-6768

10.1007/s00424-008-0508-3 doi


Action Potentials
Adrenergic beta-Agonists--pharmacology
Animals
Benzylamines--pharmacology
Calcium Signaling--drug effects
Calcium-Calmodulin-Dependent Protein Kinase Type 2--antagonists & inhibitors
Cardiac Pacing, Artificial
Cyclic AMP--analogs & derivatives
Female
Guanine Nucleotide Exchange Factors--agonists
Heart Ventricles--drug effects
Homeostasis
In Vitro Techniques
Isoproterenol--pharmacology
Isoquinolines--pharmacology
Male
Mice
Models, Cardiovascular
Myocytes, Cardiac--drug effects
Perfusion
Protein Kinase Inhibitors--pharmacology
Refractory Period, Electrophysiological
Sulfonamides--pharmacology
Tachycardia, Ventricular--metabolism
Time Factors