HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion.

Korkaya, H

HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. [electronic resource] - Oncogene Oct 2008 - 6120-30 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1476-5594

10.1038/onc.2008.207 doi


Aldehyde Dehydrogenase--analysis
Animals
Antibodies, Monoclonal--pharmacology
Antibodies, Monoclonal, Humanized
Breast--cytology
Breast Neoplasms--drug therapy
Cell Line, Tumor
Cell Proliferation
Female
Humans
Mice
Mice, Inbred NOD
Mice, SCID
Neoplasm Invasiveness
Neoplastic Stem Cells--cytology
Phosphatidylinositol 3-Kinases--physiology
Phosphoinositide-3 Kinase Inhibitors
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
Receptor, ErbB-2--physiology
Signal Transduction
Trastuzumab