miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells.

El Ouaamari, Abdelfattah

miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells. [electronic resource] - Diabetes Oct 2008 - 2708-17 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1939-327X

10.2337/db07-1614 doi


3' Untranslated Regions--genetics
3-Phosphoinositide-Dependent Protein Kinases
Animals
Base Sequence
Blotting, Western
Cell Proliferation--drug effects
Cell Survival--drug effects
Cells, Cultured
Gene Expression--drug effects
Glucose--pharmacology
Insulin--pharmacology
Insulin-Secreting Cells--cytology
Male
MicroRNAs--genetics
Oligonucleotides, Antisense--pharmacology
Phosphorylation
Protein Serine-Threonine Kinases--genetics
RNA, Messenger--genetics
Rats
Rats, Wistar
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--drug effects