Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells.

Fandy, Tamer E

Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells. [electronic resource] - Molecular cancer Jun 2008 - 60 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1476-4598

10.1186/1476-4598-7-60 doi


Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Breast Neoplasms--genetics
Caspase 3--metabolism
Cell Line, Tumor
Collagen Type XI--metabolism
Drug Resistance, Neoplasm--drug effects
Enzyme Activation--drug effects
Humans
Intracellular Signaling Peptides and Proteins--genetics
Mitochondrial Proteins--genetics
Photosensitizing Agents--pharmacology
Protein Binding
TNF-Related Apoptosis-Inducing Ligand--metabolism