In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)2] that targets integrin alphavbeta3.

Ryppa, Claudia

In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)2] that targets integrin alphavbeta3. [electronic resource] - Bioconjugate chemistry Jul 2008 - 1414-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4812

10.1021/bc800117r doi


Amino Acid Sequence
Animals
Cell Line, Tumor
Cell Proliferation--drug effects
Doxorubicin--metabolism
Endothelial Cells--cytology
Female
Humans
Integrin alphaVbeta3--metabolism
Mice
Oligopeptides--chemistry
Prodrugs--chemistry