Topoisomerase levels determine chemotherapy response in vitro and in vivo.
Burgess, Darren J
Topoisomerase levels determine chemotherapy response in vitro and in vivo. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jul 2008 - 9053-8 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.0803513105 doi
Animals
Antigens, Neoplasm--metabolism
Cell Line, Tumor
DNA Topoisomerases, Type I--metabolism
DNA Topoisomerases, Type II--metabolism
DNA-Binding Proteins--metabolism
Doxorubicin--pharmacology
Drug Resistance, Neoplasm--drug effects
Mice
Neoplasms--drug therapy
Poly-ADP-Ribose Binding Proteins
RNA Interference--drug effects
RNA, Small Interfering--metabolism
Recurrence
Topoisomerase levels determine chemotherapy response in vitro and in vivo. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jul 2008 - 9053-8 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.0803513105 doi
Animals
Antigens, Neoplasm--metabolism
Cell Line, Tumor
DNA Topoisomerases, Type I--metabolism
DNA Topoisomerases, Type II--metabolism
DNA-Binding Proteins--metabolism
Doxorubicin--pharmacology
Drug Resistance, Neoplasm--drug effects
Mice
Neoplasms--drug therapy
Poly-ADP-Ribose Binding Proteins
RNA Interference--drug effects
RNA, Small Interfering--metabolism
Recurrence