Hydralazine reduces leukocyte migration through different mechanisms in spontaneously hypertensive and normotensive rats.

Rodrigues, Stephen F

Hydralazine reduces leukocyte migration through different mechanisms in spontaneously hypertensive and normotensive rats. [electronic resource] - European journal of pharmacology Jul 2008 - 206-14 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0014-2999

10.1016/j.ejphar.2008.05.003 doi


Animals
Anti-Inflammatory Agents--pharmacology
Antihypertensive Agents--pharmacology
Blood Flow Velocity--drug effects
Blood Pressure--drug effects
Body Weight--drug effects
CD18 Antigens--metabolism
Cell Adhesion--drug effects
Cell Adhesion Molecules--genetics
Chemotaxis, Leukocyte--drug effects
Disease Models, Animal
Endothelium, Vascular--drug effects
Flow Cytometry
Hydralazine--pharmacology
Hypertension--drug therapy
Immunohistochemistry
Intercellular Adhesion Molecule-1--metabolism
L-Selectin--metabolism
Leukocyte Count
Leukocyte Rolling--drug effects
Leukocytes--drug effects
Male
Microscopy, Video
P-Selectin--metabolism
Platelet Endothelial Cell Adhesion Molecule-1--metabolism
Plethysmography
RNA, Messenger--metabolism
Rats
Rats, Inbred SHR
Rats, Wistar
Reverse Transcriptase Polymerase Chain Reaction