Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.

Chen, Peng-Chieh

Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression. [electronic resource] - PLoS genetics Jun 2008 - e1000092 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1553-7404

10.1371/journal.pgen.1000092 doi


Adenomatous Polyposis Coli Protein--genetics
Adenosine Triphosphatases--genetics
Alternative Splicing
Animals
Base Sequence
Carrier Proteins--genetics
Cell Line
Cell Movement
Cell Proliferation
Co-Repressor Proteins
Colorectal Neoplasms--genetics
Core Binding Factor Alpha 3 Subunit--genetics
DNA Mismatch Repair
DNA Repair Enzymes--genetics
DNA-Binding Proteins--genetics
Disease Progression
Female
Gene Amplification
Gene Dosage
Humans
Male
Mice
Mice, Inbred Strains
Mice, Nude
Mice, Transgenic
Mismatch Repair Endonuclease PMS2
MutL Proteins
Mutation
Neoplasm Transplantation
Protein Isoforms--genetics
Repressor Proteins--genetics
Transcription Factors--genetics
Transcriptional Activation
Transplantation, Heterologous