Cytotoxic effects of a novel pyrazolopyrimidine derivative entrapped in liposomes in anaplastic thyroid cancer cells in vitro and in xenograft tumors in vivo.
Celano, M
Cytotoxic effects of a novel pyrazolopyrimidine derivative entrapped in liposomes in anaplastic thyroid cancer cells in vitro and in xenograft tumors in vivo. [electronic resource] - Endocrine-related cancer Jun 2008 - 499-510 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1351-0088
10.1677/ERC-07-0243 doi
Animals
Annexin A5--metabolism
Apoptosis--drug effects
Cell Division--drug effects
Cell Line, Tumor
Humans
In Vitro Techniques
Liposomes--pharmacokinetics
Mice
Mice, Inbred NOD
Mice, SCID
Neoplasm Invasiveness
Pyrazoles--chemical synthesis
Pyrimidines--chemical synthesis
STAT1 Transcription Factor--drug effects
Thyroid Neoplasms--drug therapy
Triazoles--chemical synthesis
Xenograft Model Antitumor Assays
Cytotoxic effects of a novel pyrazolopyrimidine derivative entrapped in liposomes in anaplastic thyroid cancer cells in vitro and in xenograft tumors in vivo. [electronic resource] - Endocrine-related cancer Jun 2008 - 499-510 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1351-0088
10.1677/ERC-07-0243 doi
Animals
Annexin A5--metabolism
Apoptosis--drug effects
Cell Division--drug effects
Cell Line, Tumor
Humans
In Vitro Techniques
Liposomes--pharmacokinetics
Mice
Mice, Inbred NOD
Mice, SCID
Neoplasm Invasiveness
Pyrazoles--chemical synthesis
Pyrimidines--chemical synthesis
STAT1 Transcription Factor--drug effects
Thyroid Neoplasms--drug therapy
Triazoles--chemical synthesis
Xenograft Model Antitumor Assays