Immunodeficiency in ataxia telangiectasia is correlated strongly with the presence of two null mutations in the ataxia telangiectasia mutated gene.

Staples, E R

Immunodeficiency in ataxia telangiectasia is correlated strongly with the presence of two null mutations in the ataxia telangiectasia mutated gene. [electronic resource] - Clinical and experimental immunology Aug 2008 - 214-20 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1365-2249

10.1111/j.1365-2249.2008.03684.x doi


Adolescent
Adult
Antibodies, Bacterial--blood
Ataxia Telangiectasia--genetics
Ataxia Telangiectasia Mutated Proteins
B-Lymphocytes--immunology
Cell Cycle Proteins--genetics
Child
Child, Preschool
DNA-Binding Proteins--genetics
Humans
Immunoglobulin A--blood
Immunoglobulin G--analysis
Immunoglobulins, Intravenous--therapeutic use
Lymphocyte Count
Lymphopenia--genetics
Middle Aged
Mutation, Missense
Protein Serine-Threonine Kinases--genetics
Retrospective Studies
Streptococcus pneumoniae--immunology
T-Lymphocytes--immunology
Tumor Suppressor Proteins--genetics