alpha-Synuclein protofibrils inhibit 26 S proteasome-mediated protein degradation: understanding the cytotoxicity of protein protofibrils in neurodegenerative disease pathogenesis.

Zhang, Nan-Yan

alpha-Synuclein protofibrils inhibit 26 S proteasome-mediated protein degradation: understanding the cytotoxicity of protein protofibrils in neurodegenerative disease pathogenesis. [electronic resource] - The Journal of biological chemistry Jul 2008 - 20288-98 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M710560200 doi


Animals
Cattle
Neurodegenerative Diseases--metabolism
Proteasome Endopeptidase Complex--isolation & purification
Proteasome Inhibitors
Protein Binding
Protein Folding
Solubility
Ubiquitin--metabolism
alpha-Synuclein--isolation & purification