Overcoming retinoic acid-resistance of mammary carcinomas by diverting retinoic acid from PPARbeta/delta to RAR.

Schug, Thaddeus T

Overcoming retinoic acid-resistance of mammary carcinomas by diverting retinoic acid from PPARbeta/delta to RAR. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America May 2008 - 7546-51 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1091-6490

10.1073/pnas.0709981105 doi


Animals
Antineoplastic Agents--pharmacology
Carcinoma--metabolism
Cell Line, Tumor
Disease Models, Animal
Drug Resistance, Neoplasm
Fatty Acid-Binding Proteins--antagonists & inhibitors
Mammary Neoplasms, Animal--metabolism
Mice
Mice, Transgenic
Neoplasm Proteins--antagonists & inhibitors
PPAR delta--agonists
PPAR-beta--agonists
Receptors, Retinoic Acid--agonists
Transcription, Genetic--drug effects
Tretinoin--pharmacology