Microwave-enhanced alpha-arylation of a protected glycine in water: evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase.

Lagerlund, Olof

Microwave-enhanced alpha-arylation of a protected glycine in water: evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase. [electronic resource] - Combinatorial chemistry & high throughput screening Nov 2007 - 783-9 p. digital

Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't

1386-2073

10.2174/138620707783018478 doi


Catalysis
Enzyme Inhibitors--chemical synthesis
Glutamate-Ammonia Ligase--antagonists & inhibitors
Glycine--analogs & derivatives
Hydrocarbons, Cyclic--chemistry
Methionine Sulfoximine--analogs & derivatives
Microwaves
Models, Chemical
Mycobacterium tuberculosis--enzymology
Palladium--chemistry
Water--chemistry