Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction.

Tang, Qizhi

Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. [electronic resource] - Immunity May 2008 - 687-97 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1097-4180

10.1016/j.immuni.2008.03.016 doi


Animals
Autoimmunity
CD4-Positive T-Lymphocytes--cytology
Cell Survival
Diabetes Mellitus, Type 1--immunology
Interleukin-2--immunology
Interleukin-2 Receptor alpha Subunit--immunology
Islets of Langerhans--immunology
Lymph Nodes--cytology
Lymphocyte Activation
Mice
Mice, Inbred NOD
Proto-Oncogene Proteins c-bcl-2--immunology
T-Lymphocytes, Regulatory--cytology