Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum Ca load.

Desantiago, Jaime

Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum Ca load. [electronic resource] - Circulation research Jun 2008 - 1389-97 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1524-4571

10.1161/CIRCRESAHA.107.169011 doi


Adrenergic beta-Agonists--pharmacology
Adrenergic beta-Antagonists--pharmacology
Animals
Arrhythmias, Cardiac--chemically induced
Calcium--metabolism
Cells, Cultured
Disease Models, Animal
Ethanolamines--pharmacology
Female
Heart Failure--physiopathology
Heart Ventricles--cytology
Humans
Male
Myocytes, Cardiac--drug effects
Patch-Clamp Techniques
Phosphorylation--drug effects
Propanolamines--pharmacology
Rabbits
Receptors, Adrenergic, beta-2--drug effects
Sarcoplasmic Reticulum--drug effects