Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment.

Bull, S J

Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. [electronic resource] - Molecular psychiatry Dec 2009 - 1095-104 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

1476-5578

10.1038/mp.2008.48 doi


Adult
Antiviral Agents--adverse effects
Cohort Studies
Depression--chemically induced
Fatigue--chemically induced
Female
Gene Frequency
Genotype
Hepatitis C, Chronic--drug therapy
Humans
Interferon Type I--adverse effects
Interleukin-6--genetics
Male
Middle Aged
Polymorphism, Genetic
Psychiatric Status Rating Scales
Recombinant Proteins
Ribavirin--adverse effects
Serotonin Plasma Membrane Transport Proteins--genetics