Pig thrombomodulin binds human thrombin but is a poor cofactor for activation of human protein C and TAFI.

Roussel, J C

Pig thrombomodulin binds human thrombin but is a poor cofactor for activation of human protein C and TAFI. [electronic resource] - American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Jun 2008 - 1101-12 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1600-6143

10.1111/j.1600-6143.2008.02210.x doi


Animals
Carboxypeptidase B2--metabolism
Coenzymes--metabolism
Enzyme Activation
Graft Rejection--metabolism
Humans
Microcirculation
Protein Binding
Protein C--metabolism
Swine
Thrombin--metabolism
Thrombomodulin--metabolism
Thrombosis--metabolism
Transplantation, Heterologous--adverse effects