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Discovery of potent, orally bioavailable, selective 5-HT1A/B/D receptor antagonists.

Ward, Simon E

Discovery of potent, orally bioavailable, selective 5-HT1A/B/D receptor antagonists. [electronic resource] - Journal of medicinal chemistry May 2008 - 2887-90 p. digital

Publication Type: Journal Article

ISSN: 0022-2623

Standard No.: 10.1021/jm8001444 doi

Subjects--Topical Terms:
Animals
Blood-Brain Barrier--metabolism
Cerebral Cortex--metabolism
Humans
In Vitro Techniques
Piperazines--chemical synthesis
Quinolines--chemical synthesis
Radioligand Assay
Rats
Recombinant Proteins--pharmacology
Serotonin 5-HT1 Receptor Antagonists
Structure-Activity Relationship

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