Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease.

Zhang, Xiaoqun

Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease. [electronic resource] - Neuropharmacology Jun 2008 - 1143-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0028-3908

10.1016/j.neuropharm.2008.03.005 doi


Animals
Antiparkinson Agents--therapeutic use
Autoradiography--methods
Behavior, Animal
Calcium-Calmodulin-Dependent Protein Kinase Type 2--metabolism
Cocaine--analogs & derivatives
Disease Models, Animal
Dopamine--metabolism
Feedback--physiology
Functional Laterality
Gene Expression Regulation--drug effects
Levodopa--therapeutic use
Oxidopamine--toxicity
Parkinson Disease--drug therapy
Peptide Fragments--pharmacokinetics
Quinolines--pharmacology
Radioisotopes--pharmacokinetics
Rats
Rats, Sprague-Dawley
Receptors, Neurokinin-3--physiology
Serine--metabolism
Substance P--analogs & derivatives
Sympatholytics--toxicity
Tyrosine 3-Monooxygenase--metabolism