Hepatocellular binding of drugs: correction for unbound fraction in hepatocyte incubations using microsomal binding or drug lipophilicity data.

Kilford, Peter J

Hepatocellular binding of drugs: correction for unbound fraction in hepatocyte incubations using microsomal binding or drug lipophilicity data. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Jul 2008 - 1194-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-009X

10.1124/dmd.108.020834 doi


Hepatocytes--metabolism
Lipids
Microsomes, Liver--metabolism
Pharmaceutical Preparations--metabolism